Laetitia Maria Nora Anna Joachim Zita was born on 23 April 2003 at the Clinique Saint Jean in Brussels. She weighed 3.820 grammes and measured 52 cm. Upon her birth, she received the titles of Princess of Belgium and Archduchess of Austria-Este. She was born as the fifth child of Princess Astrid of Belgium, sister of King Philippe of Belgium, and Prince Lorenz of Belgium. She has two older brothers: Prince Amedeo and Prince Joachim and two older sisters: Princess Maria Laura and Princess Luisa Maria. She is currently 11th in line to the throne.
Her godparents are her older brother Prince Joachim of Belgium and Princess Nora Elisabeth of Liechtenstein, sister of Prince Hans-Adam II of Liechtenstein. Laetitia Maria has, just as her brothers and sisters, an impressive ancestry as she descends from the Austrian, Belgian, Italian, Swedish, French, Danish, British, Portuguese, Spanish and German royal families and from several Italian noble families. Her father Prince Lorenz, Archduke of Austria-Este is head of the House of Austria-Este, a branch of the formerly Imperial Austrian House of Habsburg-Lorraine.
Until the age of 12, Laetitia Maria went to the Saint John Berchmans College in Brussels where her cousins Elisabeth (future Queen of Belgium), Gabriël, Emmanuel and Eléonore also went to school. Unfortunately, there was no place for her anymore at the high school department of the St John Berchmans College. Since 2015, she has been educated at the Bromsgrove School in the United Kingdom. Her brothers and sisters also attended an English boarding school.
Princess Laetitia Maria does not accompany her parents on official engagements and lives a life outside the spotlight. Only at the inauguration of her uncle King Philippe was she seen accompanying her parents. Princess Laetitia Maria was a flower girl at the wedding of her oldest brother Prince Amedeo and Elisabetta Rosboch von Wolkenstein in 2014.